Fibronectin Growth Factor-Binding Domains Are Required for Fibroblast Survival

Fibronectin (FN) is required for embryogenesis, morphogenesis, and wound repair, and its Arg–Gly–Asp-containing central cell-binding domain (CCBD) is essential for mesenchymal cell survival and growth. Here, we demonstrate that FN contains three growth factor-binding domains (FN-GFBDs) that bind pla...

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Main Authors: Lin, Fubao, Ren, Xiang-Dong, Pan, Zhi, Macri, Lauren, Zong, Wei-Xing, Tonnesen, Marcia G., Rafailovich, Miriam, Bar-Sagi, Dafna, Clark, Richard A.F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139177/
https://ncbi.nlm.nih.gov/pubmed/20811396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.253
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