Juvenile Administration of Concomitant Methylphenidate and Fluoxetine Alters Behavioral Reactivity to Reward- and Mood-Related Stimuli and Disrupts Ventral Tegmental Area Gene Expression in Adulthood

There is a rise in the concurrent use of methylphenidate (MPH) and fluoxetine (FLX) in pediatric populations. However, the long-term neurobiological consequences of combined MPH and FLX treatment (MPH + FLX) during juvenile periods are unknown. We administered saline (VEH), MPH, FLX, or MPH + FLX to...

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Detalhes bibliográficos
Main Authors: Warren, Brandon L., Iñiguez, Sergio D., Alcantara, Lyonna F., Wright, Katherine N., Parise, Eric M., Weakley, Sarah K., Bolaños-Guzmán, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139175/
https://ncbi.nlm.nih.gov/pubmed/21753012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1470-11.2011
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