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Hyaluronic Acid and Fibrin Hydrogels with Concentrated DNA/PEI Polyplexes for Local Gene Delivery
Local delivery of DNA through a hydrogel scaffold would increase the applicability of gene therapy in tissue regeneration and cancer therapy. However, the delivery of DNA/cationic polymer nanoparticles (polyplexes) using hydrogels is challenging due to the aggregation and inactivation of polyplexes...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138902/ https://ncbi.nlm.nih.gov/pubmed/21295089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.01.028 |
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