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Chromosomal instability in mouse embryonic fibroblasts null for the transcriptional co-repressor Ski

Ski is a transcriptional regulator that has been considered an oncoprotein, given its ability to induce oncogenic transformation in avian model systems. However, studies in mouse and in some human tumor cells have also indicated a tumor suppressor activity for this protein. We found that Ski−/− mous...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marcelain, Katherine, Armisen, Ricardo, Aguirre, Adam, Ueki, Nobuhide, Toro, Jessica, Colmenares, Clemencia, Hayman, Michael J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138863/
https://ncbi.nlm.nih.gov/pubmed/21412778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22733
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