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Chiral Capillary Electrophoresis-Mass Spectrometry of DOPA: Evidence for Its Enantioselective Metabolism in PC-12 Nerve Cells

A fully automated chiral capillary electrophoresis - tandem mass spectrometric method (CE-MS/MS) was developed for enantiomeric quantification of DOPA and its precursors, phenylalanine (Phe) and tyrosine (Tyr). To avoid MS source contamination, a negatively charged chiral selector, sulfated β-cyclod...

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Detalhes bibliográficos
Main Authors: Yuan, Baiqing, Wu, Hao, Sanders, Talia, McCullum, Cassandra, Zheng, Yi, Tchounwou, Paul B., Liu, Yi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138853/
https://ncbi.nlm.nih.gov/pubmed/21683678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.05.025
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