Intranasal delivery of Norwalk virus-like particles formulated in an in-situ gelling, dry powder vaccine

The development of a vaccine to prevent norovirus infections has been focused on immunization at a mucosal surface, but has been limited by the low immunogenicity of self-assembling Norwalk virus-like particles (NV VLPs) delivered enterically or at nasal surfaces. Nasal immunization, which offers th...

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Hauptverfasser: Velasquez, Lissette S., Shira, Samantha, Berta, Alice N., Kilbourne, Jacquelyn, Medi, Babu M., Tizard, Ian, Ni, Yawei, Arntzen, Charles J., Herbst-Kralovetz, Melissa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138837/
https://ncbi.nlm.nih.gov/pubmed/21640778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.05.027
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