SPARC Stimulates Neuronal Differentiation of Medulloblastoma Cells via the Notch1/Signal Transducer and Activator of Transcription 3 (STAT3) Pathway

Secreted Protein Acidic and Rich in Cysteine (SPARC) participate in the regulation of morphogenesis and cellular differentiation through its modulation of cell-matrix interactions. We previously reported that SPARC expression significantly impairs medulloblastoma tumor growth in vivo. In this study,...

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Bibliographic Details
Main Authors: Bhoopathi, Praveen, Chetty, Chandramu, Dontula, Ranadheer, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S., Lakka, Sajani S.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138830/
https://ncbi.nlm.nih.gov/pubmed/21613407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3395
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