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Polymorphisms in the Mn-SOD and EC-SOD Genes and Their Relationship to Diabetic Neuropathy in Type 1 Diabetes Mellitus

BACKGROUND: Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy (DN). Antioxidant enzymes may protect against the rapid onset and progression of DN, by reducing the excess of OFR and peroxide. Mutatio...

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Autors principals: Chistyakov, Dimitry A, Savost'anov, Kirill V, Zotova, Elena V, Nosikov, Valery V
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC31388/
https://ncbi.nlm.nih.gov/pubmed/11299047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-2-4
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