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Microtubule remodelling is required for the front–rear polarity switch during contact inhibition of locomotion

When migrating mesenchymal cells collide, they exhibit a ‘contact inhibition of locomotion’ response that results in reversal of their front–rear polarity by extension of a new leading edge, which enables their migration away from the opposing contacted cell. The critical cytoskeletal rearrangements...

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Autores principales: Kadir, Shereen, Astin, Jonathan W., Tahtamouni, Lubna, Martin, Paul, Nobes, Catherine D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138705/
https://ncbi.nlm.nih.gov/pubmed/21750190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.087965
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