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Development of resistance to Trypanosoma cruzi in mice depends on a viable population of L3T4+ (CD4+) T lymphocytes.
Mice injected with monoclonal antibody to the L3T4+ (CD4+) cell membrane surface glycoprotein of T lymphocytes and immunized with antigens of Trypanosoma cruzi had reduced antibody and cell-mediated immune responses to the organism. Mortality in these mice was 100% following challenge with 1.5 x 10(...
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主要作者: | |
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格式: | Artigo |
語言: | Inglês |
出版: |
1989
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313867/ https://ncbi.nlm.nih.gov/pubmed/2499547 |
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