Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation, and Long-Term Memory

To identify the role of the histone acetyltransferase (HAT) CREB-binding protein (CBP) in neurons of the CA1 region of the hippocampus during memory formation, we examine the effects of a focal homozygous knockout of CBP on histone modifications, gene expression, synaptic plasticity, and long-term m...

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Detalhes bibliográficos
Main Authors: Barrett, Ruth M, Malvaez, Melissa, Kramar, Eniko, Matheos, Dina P, Arrizon, Abraham, Cabrera, Sara M, Lynch, Gary, Greene, Robert W, Wood, Marcelo A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138668/
https://ncbi.nlm.nih.gov/pubmed/21508930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.61
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