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Pharmacological Stimulation of Locus Coeruleus Reveals a New Antipsychotic-Responsive Pathway for Deficient Sensorimotor Gating

Surprisingly little is known about the modulation of core endophenotypes of psychiatric disease by discrete noradrenergic (NE) circuits. Prepulse inhibition (PPI), the diminution of startle responses when weak prestimuli precede the startling event, is a widely validated translational paradigm for i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alsene, Karen M, Bakshi, Vaishali P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138657/
https://ncbi.nlm.nih.gov/pubmed/21508929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.47
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