Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

In the search for antidepressants' (ADs') mechanisms of action beyond their influence on monoaminergic neurotransmission, we analyzed the effects of three structurally and pharmacologically different ADs on autophagic processes in rat primary astrocytes and neurons. Autophagy has a signifi...

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Autors principals: Zschocke, Jürgen, Zimmermann, Nicole, Berning, Barbara, Ganal, Vanessa, Holsboer, Florian, Rein, Theo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138654/
https://ncbi.nlm.nih.gov/pubmed/21508931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.57
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