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Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

In the search for antidepressants' (ADs') mechanisms of action beyond their influence on monoaminergic neurotransmission, we analyzed the effects of three structurally and pharmacologically different ADs on autophagic processes in rat primary astrocytes and neurons. Autophagy has a signifi...

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Detalhes bibliográficos
Main Authors: Zschocke, Jürgen, Zimmermann, Nicole, Berning, Barbara, Ganal, Vanessa, Holsboer, Florian, Rein, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138654/
https://ncbi.nlm.nih.gov/pubmed/21508931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.57
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