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Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

In the search for antidepressants' (ADs') mechanisms of action beyond their influence on monoaminergic neurotransmission, we analyzed the effects of three structurally and pharmacologically different ADs on autophagic processes in rat primary astrocytes and neurons. Autophagy has a signifi...

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Bibliografiske detaljer
Main Authors: Zschocke, Jürgen, Zimmermann, Nicole, Berning, Barbara, Ganal, Vanessa, Holsboer, Florian, Rein, Theo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138654/
https://ncbi.nlm.nih.gov/pubmed/21508931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.57
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