Inhibition of Mer and Axl Receptor Tyrosine Kinases in Astrocytoma Cells Leads to Increased Apoptosis and Improved Chemosensitivity

Astrocytomas account for the majority of malignant brain tumors diagnosed in both adult and pediatric patients. The therapies available to treat these neoplasms are limited, and the prognosis associated with high-grade lesions is extremely poor. Mer (MerTK) and Axl receptor tyrosine kinases (RTK) ar...

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Autori principali: Keating, Amy K., Kim, Grace K., Jones, Ashley E., Donson, Andrew M., Ware, Kathryn, Mulcahy, Jean M., Salzberg, Dana B., Foreman, Nicholas K., Liang, Xiayuan, Thorburn, Andrew, Graham, Douglas K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138539/
https://ncbi.nlm.nih.gov/pubmed/20423999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0707
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