Short-Term Fenofibrate Treatment Reduces Elevated Plasma Lp-PLA(2) Mass and sVCAM-1 Levels in a Sub-Cohort of Hypertriglyceridemic GOLDN Participants

BACKGROUND: High levels of lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) are associated with inflammation, atherosclerosis, and CHD events. In addition, Lp-PLA(2) has been linked to classical markers of endothelial activation, including soluble vascular cell adhesion molecule-1 (sVCAM-1). Th...

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Autores principales: Tsai, Alexander K., Steffen, Brian T., Ordovas, Jose M., Straka, Robert, Zhou, Xia, Hanson, Naomi Q, Arnett, Donna, Tsai, Michael Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138503/
https://ncbi.nlm.nih.gov/pubmed/21757154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2011.01.014
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