Calcium is required for the expression of anthrax lethal toxin activity in the macrophagelike cell line J774A.1.

Anthrax lethal toxin, which consists of two separate proteins, protective antigen (Mr, 82,700) and lethal factor (Mr, approximately 83,000), is cytotoxic to the macrophagelike cell line J774A.1. Removal of calcium from the culture medium protected cells against the action of lethal toxin. Calcium de...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Bhatnagar, R, Singh, Y, Leppla, S H, Friedlander, A M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2499545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.7.2107-2114.1989
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