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A local glucose-and oxygen concentration-based insulin secretion model for pancreatic islets

BACKGROUND: Because insulin is the main regulator of glucose homeostasis, quantitative models describing the dynamics of glucose-induced insulin secretion are of obvious interest. Here, a computational model is introduced that focuses not on organism-level concentrations, but on the quantitative mod...

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Bibliographic Details
Main Author: Buchwald, Peter
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138450/
https://ncbi.nlm.nih.gov/pubmed/21693022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-8-20
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