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Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise

We tested the hypothesis that peripheral blood mononuclear cells (PBMC) of older adults demonstrate a proinflammatory/-oxidative gene expression profile that can be improved by regular aerobic exercise. PBMC were isolated from young (n = 25, 18–33 yr) and middle-aged/older (n = 40, 50–76 yr) healthy...

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Detalhes bibliográficos
Main Authors: Gano, Lindsey B., Donato, Anthony J., Pierce, Gary L., Pasha, Hamza M., Magerko, Katherine A., Roeca, Cassandra, Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138336/
https://ncbi.nlm.nih.gov/pubmed/21610086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00204.2010
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