Optogenetic Control of Motor Coordination by G(i/o) Protein-coupled Vertebrate Rhodopsin in Cerebellar Purkinje Cells

G protein-coupled receptors are involved in the modulation of complex neuronal networks in the brain. To investigate the impact of a cell-specific G(i/o) protein-mediated signaling pathway on brain function, we created a new optogenetic mouse model in which the G(i/o) protein-coupled receptor verteb...

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Detalhes bibliográficos
Main Authors: Gutierrez, Davina V., Mark, Melanie D., Masseck, Olivia, Maejima, Takashi, Kuckelsberg, Denise, Hyde, Robert A., Krause, Martin, Kruse, Wolfgang, Herlitze, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138296/
https://ncbi.nlm.nih.gov/pubmed/21628464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253674
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