Fibroblast Growth Factor-12 (FGF12) Translocation into Intestinal Epithelial Cells Is Dependent on a Novel Cell-penetrating Peptide Domain: INVOLVEMENT OF INTERNALIZATION IN THE IN VIVO ROLE OF EXOGENOUS FGF12

The extracellular effect of fibroblast growth factor-12 (FGF12) remains unknown because FGF12 cannot activate any fibroblast growth factor receptors (FGFRs), and FGF12 is not currently thought to be released from cells. We reported previously that FGF12 plays an intracellular role in the inhibition...

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Autores principales: Nakayama, Fumiaki, Yasuda, Takeshi, Umeda, Sachiko, Asada, Masahiro, Imamura, Toru, Meineke, Viktor, Akashi, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138292/
https://ncbi.nlm.nih.gov/pubmed/21518765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198267
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