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Prenylated C17orf37 Induces Filopodia Formation to Promote Cell Migration and Metastasis

Post-translational modification by covalent attachment of isoprenoid lipids (prenylation) regulates the functions and biological activities of several proteins implicated in the oncogenic transformation and metastatic progression of cancer. The largest group of prenylated proteins contains a CAAX mo...

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Autori principali: Dasgupta, Subhamoy, Cushman, Ian, Kpetemey, Marilyne, Casey, Patrick J., Vishwanatha, Jamboor K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138290/
https://ncbi.nlm.nih.gov/pubmed/21628459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254599
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