Kallikrein-related Peptidase 12 Hydrolyzes Matricellular Proteins of the CCN Family and Modifies Interactions of CCN1 and CCN5 with Growth Factors

Kallikrein-related peptidases (KLKs) are an emerging group of secreted serine proteases involved in several physiological and pathological processes. We used a degradomic approach to identify potential substrates of KLK12. MDA-MB-231 cells were treated either with KLK12 or vehicle control, and the p...

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Main Authors: Guillon-Munos, Audrey, Oikonomopoulou, Katerina, Michel, Noémie, Smith, Chistopher R., Petit-Courty, Agnès, Canepa, Sylvie, Reverdiau, Pascale, Heuzé-Vourc'h, Nathalie, Diamandis, Eleftherios P., Courty, Yves
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138267/
https://ncbi.nlm.nih.gov/pubmed/21628462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213231
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