Structural Basis of Rnd1 Binding to Plexin Rho GTPase Binding Domains (RBDs)

Plexin receptors regulate cell adhesion, migration, and guidance. The Rho GTPase binding domain (RBD) of plexin-A1 and -B1 can bind GTPases, including Rnd1. By contrast, plexin-C1 and -D1 reportedly bind Rnd2 but associate with Rnd1 only weakly. The structural basis of this differential Rnd1 GTPase...

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Detalhes bibliográficos
Main Authors: Wang, Hui, Hota, Prasanta K., Tong, Yufeng, Li, Buren, Shen, Limin, Nedyalkova, Lyudmila, Borthakur, Susmita, Kim, SoonJeung, Tempel, Wolfram, Buck, Matthias, Park, Hee-Won
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138255/
https://ncbi.nlm.nih.gov/pubmed/21610070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197053
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