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Mechanisms of Estradiol-Induced Insulin Secretion by the G Protein-Coupled Estrogen Receptor GPR30/GPER in Pancreatic β-Cells

Sexual dimorphism and supplementation studies suggest an important role for estrogens in the amelioration of glucose intolerance and diabetes. Because little is known regarding the signaling mechanisms involved in estradiol-mediated insulin secretion, we investigated the role of the G protein-couple...

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Autori principali: Sharma, Geetanjali, Prossnitz, Eric R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138237/
https://ncbi.nlm.nih.gov/pubmed/21673097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-0091
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