Mechanisms of Estradiol-Induced Insulin Secretion by the G Protein-Coupled Estrogen Receptor GPR30/GPER in Pancreatic β-Cells

Sexual dimorphism and supplementation studies suggest an important role for estrogens in the amelioration of glucose intolerance and diabetes. Because little is known regarding the signaling mechanisms involved in estradiol-mediated insulin secretion, we investigated the role of the G protein-couple...

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Bibliographic Details
Main Authors: Sharma, Geetanjali, Prossnitz, Eric R.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138237/
https://ncbi.nlm.nih.gov/pubmed/21673097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-0091
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