Electroporation Mediated Delivery of a Naked DNA Plasmid Expressing VEGF to the Porcine Heart Enhances Protein Expression

Gene therapy is an attractive method for the treatment of cardiovascular disease. However, using current strategies, induction of gene expression at therapeutic levels is often inefficient. In this study, we demonstrate a novel electroporation method to enhance delivery of a plasmid expressing an an...

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Detalhes bibliográficos
Main Authors: Marshall, William G., Boone, Brian A., Burgos, Jose D., Gografe, Sylvia I., Baldwin, Margaret K., Danielson, Michele L., Larson, Mary J., Caretto, Denise R., Cruz, Yolmari, Ferraro, Bernadette, Heller, Loree C., Ugen, Kenneth E., Jaroszeski, Mark J., Heller, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138211/
https://ncbi.nlm.nih.gov/pubmed/19956270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.153
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