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Delineating an Epigenetic Continuum for Initiation, Transformation and Progression to Breast Cancer

Aberrant methylation of promoter CpG islands is a hallmark of human cancers and is an early event in carcinogenesis. We examined whether promoter hypermethylation contributes to the pathogenesis of benign breast lesions along a progression continuum to invasive breast cancer. The exploratory study c...

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Detalhes bibliográficos
Main Authors: Chen, Kang Mei, Stephen, Josena K., Raju, Usha, Worsham, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138135/
https://ncbi.nlm.nih.gov/pubmed/21776373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3021580
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