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COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method

Motivation: The identification of condition specific sub-networks from gene expression profiles has important biological applications, ranging from the selection of disease-related biomarkers to the discovery of pathway alterations across different phenotypes. Although many methods exist for extract...

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Detalhes bibliográficos
Main Authors: Ma, Haisu, Schadt, Eric E., Kaplan, Lee M., Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138081/
https://ncbi.nlm.nih.gov/pubmed/21414987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr136
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