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Endothelial Cells in Co-culture Enhance Embryonic Stem Cell Differentiation to Pancreatic Progenitors and Insulin-Producing Cells through BMP Signaling

Endothelial cells (ECs) represent the major component of the embryonic pancreatic niche and play a key role in the differentiation of insulin-producing β cells in vivo. However, it is unknown if ECs promote such differentiation in vitro. We investigated whether interaction of ECs with mouse embryoid...

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Detalhes bibliográficos
Main Authors: Talavera-Adame, Dodanim, Wu, Gordon, He, Yao, Ng, Tina T., Gupta, Ankur, Kurtovic, Silvia, Hwang, Jae Y., Farkas, Daniel L., Dafoe, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Humana Press Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137775/
https://ncbi.nlm.nih.gov/pubmed/21298405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-011-9232-z
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