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The cerebellar GABA(A)R α6 R100Q polymorphism alters ligand binding in outbred Sprague-Dawley rats in a similar manner as in selectively bred AT and ANT rats
The alcohol-tolerant AT and -non-tolerant ANT rat lines have been selectively bred for innate sensitivity to ethanol-induced motor impairment. The cerebellar GABA(A) receptor α6 subunit alleles α6-100R and α6-100Q are segregated in the AT and ANT rats, respectively. This α6 polymorphism might explai...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137752/ https://ncbi.nlm.nih.gov/pubmed/21163615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2010.11.003 |
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