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Chemical ‘Jekyll and Hyde’s: Small-molecule inhibitors of developmental signaling pathways

Small molecules that perturb developmental signaling pathways can have devastating effects on embryonic patterning, as evidenced by the chemically induced onset of cyclopic lambs and children with severely shortened limbs during the 1950s. Recent studies, however, have revealed critical roles for th...

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Detalhes bibliográficos
Main Authors: Sakata, Tomoyo, Chen, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137710/
https://ncbi.nlm.nih.gov/pubmed/21505654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cs15019g
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