Vascular and extravascular immunoreactivity for Intercellular Adhesion Molecule 1 in the orbitofrontal cortex of subjects with major depression: age-dependent changes

BACKGROUND: Vascular and immune alterations in the prefrontal cortex may contribute to major depression in elderly subjects. Intercellular adhesion molecule-1 (ICAM-1), major inflammatory mediator in vessels and astrocytes, could be altered in geriatric depression, but little is known about its age-...

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Autores principales: Miguel-Hidalgo, Jose Javier, Overholser, James C., Jurjus, George J., Meltzer, Herbert Y., Dieter, Lesa, Konick, Lisa, Stockmeier, Craig A., Rajkowska, Grazyna
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137705/
https://ncbi.nlm.nih.gov/pubmed/21536333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2011.03.052
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