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Accelerating Haplotype-Based Genome-Wide Association Study Using Perfect Phylogeny and Phase-Known Reference Data

The genome-wide association study (GWAS) has become a routine approach for mapping disease risk loci with the advent of large-scale genotyping technologies. Multi-allelic haplotype markers can provide superior power compared with single-SNP markers in mapping disease loci. However, the application o...

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Autori principali: He, Yungang, Li, Cong, Amos, Christopher I., Xiong, Momiao, Ling, Hua, Jin, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137625/
https://ncbi.nlm.nih.gov/pubmed/21789217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022097
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