Generation of Germline-Competent Rat Induced Pluripotent Stem Cells

BACKGROUND: Recent progress in rat pluripotent stem cell technology has been remarkable. Particularly salient is the demonstration that embryonic stem cells (ESCs) in the rat (rESCs) can contribute to germline transmission, permitting generation of gene-modified rats as is now done using mouse ESCs...

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Détails bibliographiques
Auteurs principaux: Hamanaka, Sanae, Yamaguchi, Tomoyuki, Kobayashi, Toshihiro, Kato-Itoh, Megumi, Yamazaki, Satoshi, Sato, Hideyuki, Umino, Ayumi, Wakiyama, Yukiko, Arai, Mami, Sanbo, Makoto, Hirabayashi, Masumi, Nakauchi, Hiromitsu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137610/
https://ncbi.nlm.nih.gov/pubmed/21789202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022008
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