Generation of Germline-Competent Rat Induced Pluripotent Stem Cells

BACKGROUND: Recent progress in rat pluripotent stem cell technology has been remarkable. Particularly salient is the demonstration that embryonic stem cells (ESCs) in the rat (rESCs) can contribute to germline transmission, permitting generation of gene-modified rats as is now done using mouse ESCs...

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Detalhes bibliográficos
Main Authors: Hamanaka, Sanae, Yamaguchi, Tomoyuki, Kobayashi, Toshihiro, Kato-Itoh, Megumi, Yamazaki, Satoshi, Sato, Hideyuki, Umino, Ayumi, Wakiyama, Yukiko, Arai, Mami, Sanbo, Makoto, Hirabayashi, Masumi, Nakauchi, Hiromitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137610/
https://ncbi.nlm.nih.gov/pubmed/21789202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022008
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