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Using an Uncertainty-Coding Matrix in Bayesian Regression Models for Haplotype-Specific Risk Detection in Family Association Studies

Haplotype association studies based on family genotype data can provide more biological information than single marker association studies. Difficulties arise, however, in the inference of haplotype phase determination and in haplotype transmission/non-transmission status. Incorporation of the uncer...

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Библиографические подробности
Главные авторы: Huang, Yung-Hsiang, Lee, Mei-Hsien, Chen, Wei J., Hsiao, Chuhsing Kate
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137600/
https://ncbi.nlm.nih.gov/pubmed/21789192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021890
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