Cold-Adapted Influenza and Recombinant Adenovirus Vaccines Induce Cross-Protective Immunity against pH1N1 Challenge in Mice

BACKGROUND: The rapid spread of the 2009 H1N1 pandemic influenza virus (pH1N1) highlighted problems associated with relying on strain-matched vaccines. A lengthy process of strain identification, manufacture, and testing is required for current strain-matched vaccines and delays vaccine availability...

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Main Authors: Soboleski, Mark R., Gabbard, Jon D., Price, Graeme E., Misplon, Julia A., Lo, Chia-Yun, Perez, Daniel R., Ye, Jianqiang, Tompkins, S. Mark, Epstein, Suzanne L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137593/
https://ncbi.nlm.nih.gov/pubmed/21789196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021937
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