Increased tumor necrosis factor-α, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the β(1)-adrenergic receptor knockout mouse

PURPOSE: To investigate the role of β1-adrenergic receptors on insulin like growth factor (IGF)-1 receptor signaling and apoptosis in the retina using β1-adrenergic receptor knockout (KO) mice. METHODS: Western blotting and enzyme-linked immunosorbent assay analyses were done on whole retinal lysate...

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Main Authors: Panjala, Surekha Rani, Jiang, Youde, Kern, Timothy S., Thomas, Steven A., Steinle, Jena J.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137556/
https://ncbi.nlm.nih.gov/pubmed/21850156
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