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HOXC11–SRC-1 regulation of S100beta in cutaneous melanoma: new targets for the kinase inhibitor dasatinib

BACKGROUND: Cutaneous melanoma is an aggressive disease. S100beta is an established biomarker of disease progression; however, the mechanism of its regulation in melanoma is undefined. METHODS: Expression of HOXC11 and SRC-1 was examined by immunohistochemistry and immunofluorescence. Molecular and...

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Detalhes bibliográficos
Main Authors: deBlacam, C, Byrne, C, Hughes, E, McIlroy, M, Bane, F, Hill, A D K, Young, L S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137411/
https://ncbi.nlm.nih.gov/pubmed/21654685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.193
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