Fab fragments from a monoclonal antibody against a germ tube mannoprotein block the yeast-to-mycelium transition in Candida albicans.

Fab fragments prepared from the immunoglobulin G monoclonal antibody (MAb) 4C12, which reacts with a determinant expressed on the hyphal extension of germ tubes of Candida albicans, inhibited germ tube formation, but intact MAb 4C12 did not. Indirect immunofluorescence showed a punctate binding patt...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Casanova, M, Martínez, J P, Chaffin, W L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2228250/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3810-3812.1990
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