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Pimavanserin tartrate, a 5-HT(2A) Receptor Inverse Agonist, Increases Slow Wave Sleep as Measured by Polysomnography in Healthy Adult Volunteers

OBJECTIVE: Determine the effects of pimavanserin tartrate [ACP-103; N-(4-flurophenylmethyl)-N-(1-methylpiperidin-4-yl)-N’-(4-(2-methylpropyloxy)phenylmethyl)carbamide], a selective serotonin 5-HT(2A) receptor inverse agonist, on slow wave sleep (SWS), other sleep parameters, and attention/vigilance....

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Detalhes bibliográficos
Main Authors: Ancoli-Israel, Sonia, Vanover, Kimberly E., Weiner, David M., Davis, Robert E., van Kammen, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137254/
https://ncbi.nlm.nih.gov/pubmed/21256805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sleep.2010.10.004
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