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Structure of QnrB1, a Plasmid-mediated Fluoroquinolone Resistance Factor

QnrB1 is a plasmid-encoded pentapeptide repeat protein (PRP) that confers a moderate degree of resistance to fluoroquinolones. Its gene was cloned into an expression vector with an N-terminal polyhistidine tag, and the protein was purified by nickel affinity chromatography. The structure of QnrB1 wa...

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Main Authors: Vetting, Matthew W., Hegde, Subray S., Wang, Minghua, Jacoby, George A., Hooper, David C., Blanchard, John S.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137097/
https://ncbi.nlm.nih.gov/pubmed/21597116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226936
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