Cap2-HAP Complex Is a Critical Transcriptional Regulator That Has Dual but Contrasting Roles in Regulation of Iron Homeostasis in Candida albicans

Iron homeostasis is highly regulated in organisms across evolutionary time scale as iron is essential for various cellular processes. In a computational screen, we identified the Yap/bZIP domain family in Candida clade genomes. Cap2/Hap43 is essential for C. albicans growth under iron-deprivation co...

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Bibliographic Details
Main Authors: Singh, Rana Pratap, Prasad, Himanshu K., Sinha, Ishani, Agarwal, Neha, Natarajan, Krishnamurthy
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137088/
https://ncbi.nlm.nih.gov/pubmed/21592964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233569
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