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Adenylate cyclase toxin of Bordetella pertussis: production, purification, and partial characterization.

Bordetella pertussis produces a number of virulence determinants which contribute to its pathogenicity. One factor, the adenylate cyclase toxin (ACT), has been suggested to directly penetrate human phagocytes and disrupt their normal function by direct production of intracellular cyclic AMP (cAMP)....

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Leusch, M S, Paulaitis, S, Friedman, R L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2228232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3621-3626.1990
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