Characterization of a Central Ca(2+)/Calmodulin-dependent Protein Kinase IIα/β Binding Domain in Densin That Selectively Modulates Glutamate Receptor Subunit Phosphorylation

The densin C-terminal domain can target Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) in cells. Although the C-terminal domain selectively binds CaMKIIα in vitro, full-length densin associates with CaMKIIα or CaMKIIβ in brain extracts and in transfected HEK293 cells. This interaction requ...

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Hlavní autoři: Jiao, Yuxia, Jalan-Sakrikar, Nidhi, Robison, A. J., Baucum, Anthony J., Bass, Martha A., Colbran, Roger J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137056/
https://ncbi.nlm.nih.gov/pubmed/21610080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216010
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