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Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions

Rap1 is a Ras-like GTPase that has been studied with respect to its role in cadherin-based cell adhesion. Rap1 exists as two separate isoforms, Rap1A and Rap1B, which are 95% identical and yet the phenotype of the isoform-specific knockout mice is different. We and others have previously identified...

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Detalhes bibliográficos
Main Authors: Wittchen, Erika S, Aghajanian, Amir, Burridge, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136906/
https://ncbi.nlm.nih.gov/pubmed/21776404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.2.15735
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