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Differential occurrence of protein intrinsic disorder in the cytoplasmic signaling domains of cell receptors

In human membrane proteins, intrinsically disordered regions, the regions that lack a well-defined three-dimensional structure under physiological conditions, preferentially occur in the cytoplasmic tails. Many of these proteins represent cell receptors that function by recognizing their cognate lig...

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Autori principali: Sigalov, Alexander B, Uversky, Vladimir N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136905/
https://ncbi.nlm.nih.gov/pubmed/21776336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.2.1.14790
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