Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

Fibroblastic growth factor 23 (FGF23) is a circulating phosphaturic hormone. Inactivating mutations of the endopeptidase PHEX or the SIBLING protein DMP1 result in equivalent intrinsic bone mineralization defects and increased Fgf23 expression in osteocytes. The mechanisms whereby PHEX and DMP1 regu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Martin, Aline, Liu, Shiguang, David, Valentin, Li, Hua, Karydis, Anastasios, Feng, Jian Q., Quarles, L. Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136343/
https://ncbi.nlm.nih.gov/pubmed/21507898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-177816
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados