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Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli
A triazole mimic of a DNA phosphodiester linkage has been produced by templated chemical ligation of oligonucleotides functionalized with 5′-azide and 3′-alkyne. The individual azide and alkyne oligonucleotides were synthesized by standard phosphoramidite methods and assembled using a straightforwar...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136318/ https://ncbi.nlm.nih.gov/pubmed/21709264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101519108 |
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