Membrane tension regulates motility by controlling lamellipodium organization

Many cell movements proceed via a crawling mechanism, where polymerization of the cytoskeletal protein actin pushes out the leading edge membrane. In this model, membrane tension has been seen as an impediment to filament growth and cell motility. Here we use a simple model of cell motility, the Cae...

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Bibliographic Details
Main Authors: Batchelder, Ellen L., Hollopeter, Gunther, Campillo, Clément, Mezanges, Xavier, Jorgensen, Erik M., Nassoy, Pierre, Sens, Pierre, Plastino, Julie
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136290/
https://ncbi.nlm.nih.gov/pubmed/21709265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010481108
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