Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle

Myosin-binding protein C (MyBP-C) is a thick filament protein playing an essential role in muscle contraction, and MyBP-C mutations cause heart and skeletal muscle disease in millions worldwide. Despite its discovery 40 y ago, the mechanism of MyBP-C function remains unknown. In vitro studies sugges...

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Bibliographic Details
Main Authors: Luther, Pradeep K., Winkler, Hanspeter, Taylor, Kenneth, Zoghbi, Maria E., Craig, Roger, Padrón, Raúl, Squire, John M., Liu, Jun
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136262/
https://ncbi.nlm.nih.gov/pubmed/21705660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103216108
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